Top Menu


About Nashoba Valley Dental

A Full-Service, Progressive Dental Practice

Nashoba Valley Dental was founded on the idea that everyone should have a smile they love. Our services include anything from patching a tooth to a complete smile makeover – and everything in between. In taking over this dental practice that has served as a staple in the community for years, Dr. Matthew Annese stayed in line with the previous practice owner’s philosophy of patient education and involvement. Add that to a vast selection of services and use of the latest innovations in dental technology, and we help patients get the smile they always wanted in the way that works best for them.

Our dental professionals are driven by a commitment to deliver the highest-quality dental work in a setting that is familiar and relaxed. We never push patients to get treatment they aren’t comfortable with, and if the ideal solution doesn’t work with their budget, we find an alternative that produces results that are just as desirable. Dr. Annese and our staff have created a culture that is energetic, yet laid back, and proactive, yet resourceful. We want everyone coming into our office to feel at ease, which is why, on top of exceptional dental care, we offer comforts such as TV’s for entertainment and a coffee station for our patients to enjoy while waiting they wait. Your peace of mind is our priority.

Take a Virtual Tour of Nashoba Valley Dental

See our practice before you step through our doors with our virtual tour! You can get a feel for the front office, the operatories, and our general location so you feel more comfortable during your first visit.


About Dr. Annese

Dr. Annese grew up in nearby Billerica, Massachusetts. Having spent his summers working construction, he was able to dedicate numerous hours to the rebuilding effort of New Orleans after Hurricane Katrina. These experiences made him realize that he truly enjoyed helping those in need. When exploring professions, he searched for a field where he could have a direct impact on people. Dentistry called to him as he realized how much a confident smile could change someone’s life.

Since graduating from Boston University School of Dental Medicine, Dr. Annese retains faculty status at Boston University and Tufts School of Dental Medicine. Every year he surpasses the required education hours to ensure he stays abreast of the latest technologies and techniques. He also prefers to work closely with patients when evaluating their needs, always giving them a voice in their treatment plan and aiming to deliver services as quickly and comfortably as possible.

Outside of the office, Dr. Annese enjoys spending time with his wife, Allison, and family. He especially enjoys watching his little guy, Bennett, grow up way too fast. He stays active with hockey, exercise, water sports, and skiing – but also enjoys putting calories back on with new restaurants, wine and craft beer.

About Dr. Byer

Dr. Nicole Byer joined Nashoba Valley Dental in 2018. Originally from New Hampshire and raised by parents who are health professionals, she knew she also wanted to join the healthcare field. She gravitated towards dentistry in order to have a direct and meaningful impact on patients’ oral and overall health. Dr. Byer completed her undergraduate education at Tufts University in Medford, MA and then moved to Philadelphia, PA to attend dental school at the University of Pennsylvania School of Dental Medicine. She wanted to return to New England after school and pursued a General Practice Residency at the Massachusetts General Hospital. Through her education, she gained a wealth of experience in clinical dentistry as well as managing medically complex patients. She continues to pursue new knowledge and stays up to date on the ever-changing dental field through continuing education. Dr. Byer believes in providing quality and ethical dental care for her patients by always leading with compassion. Outside of the office, Dr. Byer enjoys spending time with family and friends, cooking, and walking around Boston and in nature.

Our Team

When you walk into Nashoba Valley Dental, you will be greeted with a warm welcome by one of our incredible staff members. We have a lot of energy and genuine excitement for helping people love their teeth! From our dental assistants to our hygienists and administrative specialists, we all share a common goal of making our patients feel comfortable and well-served. With a motivating outlook and desire to change the industry with the best in technology, each member of our team follows the lead of Dr. Annese and puts the patients first, making sure they always understand their dental needs and treatment options.


Registered Dental Hygienist

Jackie joined the practice in 2015. She grew up in rural northeastern Vermont and graduated from the University of Vermont with a Dental Hygiene Degree in 2004. During school, Jackie was elected president of UVM’s Student American Dental Hygiene Association and was inducted into the Sigma Phi Alpha dental hygiene honor society. She was also a member of UVM and Vermont Technical College’s advisory committees for several years.

Jackie’s interest in dentistry began at a young age when she would go to work with her mother as a “helper”. She later went on to work as a dental office manager for eight years until she was able to pursue her dream of becoming a dental hygienist. She’s driven to help patients achieve and maintain their oral health in a compassionate and comfortable environment. When she’s not working, Jackie’s most cherished time is spent with her family. She also enjoys baking and spending long days at the beach!


Registered Dental Hygienist

Kayla has always been interested in dentistry and oral health. Her first job while in high school was at a dental office, where she realized that a career in dental hygiene would be perfect for her. Kayla graduated Middlesex Community College with an Associate of Science degree in Dental Hygiene and has been working with Dr. Annese since 2014.

There are numerous things about being a dental hygienist that make Kayla’s job rewarding. She loves meeting new people from various backgrounds and forming relationships with them while catching up (and celebrating their progress) every six months at their visits. She also enjoys the educational aspect of her profession – helping patients understand how oral health is related to their overall well-being and motivating them to improve their oral hygiene. Her advocacy even brought her to Peru in 2013, where she educated remote villages correct dental practices and the importance of maintaining good oral health.

Being compassionate, understanding, and helpful with her patients is important to Kayla.. She lives these traits outside of work as well, where she is passionate about the environment and a dedicated animal rescuer. She even has two rescue cats, Milly and Milo.


Registered Dental Hygienist

Kelley has 24 years of experience in clinical dental hygiene practice. She obtained a Bachelor’s Degree in Dental Hygiene from Northeastern University in 1994 and a Graduate Certificate in Advanced DentalHygiene Science from The Forsyth School for Dental Hygienists in Boston, MA in1995. She is currently pursuing a Master’s Degree in Dental Hygiene Education from Massachusetts College of Pharmacy and Health Sciences in Boston, MA.

Kelley has vast experience and knowledge in all aspects of dental hygiene practice with a special concentration in preventive dental hygiene care and non-surgical periodontal therapy.

In addition to her clinical practice, Kelley is an adjunct clinical Dental Hygiene Instructor at Mt. Wachusett Community College.

Kelley lives in Lunenburg with her husband and three daughters. In her spare time, she enjoys reading, hiking with her family, and attending her daughters’ many sporting events.



Insurance Coordinator


Dental Assistant

Jena is one of our dental assistants, she brings a light-hearted sense of humor to the office, she likes to make patients smile and make their time with us comfortable and enjoyable. She started working in the dental field in 2007 and has grown with the career ever since. She has experience in both clinical and business aspects of dentistry and is fortunate enough to love her line of work. Some of her most memorable experiences are dental volunteer trips to third world countries. Through these experiences she has learned to further appreciate her life and career, finding it rewarding and awakening. In her free time she enjoys going to her families home in Canada and boating on Lake Winnipesaukee with family and friends.



Practice Coordinator

Deborah has been working at this location for more than 14 years. She started as a Certified Dental Assistant and in the past year has changed her position in the office toPractice Director and Treatment Plan Coordinator. Deborah enjoys that she still has the ability to interact with patients in her new role.

Deborah likes spending time with her family and friends as well as traveling to new places. She also loves to learn new things and is currently working on a degree in Business Management.



Office Manager

Ann has worked in the front office at this location for nine years, first as a receptionist and now as the office manager. One of her favorite things about working in dentistry is getting to know the patients and seeing their smile transformations from beginning to end. In her spare time, Ann enjoys planning vacations, shopping at Target, and, most of all, spending time with her husband and young daughter.




Dental Assistant

We are proud to offer gentle nitrous sedation for children who may have worries or anxieties about visiting the dentist.

Pediatric Services

Curious about getting straighter teeth? Dr. Annese is a certified Invisalign provider. Come in for a smile makeover today!

Cosmetic Dentistry

Nashoba Valley Dental offers in-office tooth extractions, and is here to help with any dental emergencies.

Restorative Services

“Working With Patients to Create Healthy Smiles,
For Life”

- Dr. Matthew Annese


Our office is located about 30 miles outside of Boston, in Shirley, MA. We offer full-service dental care to the entire local community.

Our Location

Review our payment options to see if your insurance is in network. If not, we will work with your provider to set a fair cost.


We offer family, cosmetic, and restorative dentistry, and use the latest technology to meet all your dental care needs.

Our Services